The article investigates the impact of international factors to formation of marketing adaptation strategies of regional centres development; regards influence of “regional revolution” to strategic trends of cities of Chernivtsi and Suceava; forms a list of factors that can either open additional opportunities for a city or, on the contrary, become potential bearers of threats for implementation of sustainable development strategy; attention is paid to threats and advantages for regional economy of activation processes of activity of global trade networks; examples of cooperation in geo-space direction are given; the role of regional marketing technologies is determined in provision of complex long-term cross-border effect of cooperation of Chernivtsi and Suceava as regional centres of Bukovyna.